Evaluation of The Antidepressant Properties of Aqueous Extract Terminalia Chebula Fruit Pulp in Wistar Albino Rats.

Between 9 and 46% of those being treated for major depressive disorder had a partial or no response to antidepressants. Research is needed produce more effective safer antidepressant. Terminalia chebula stimulates the CNS. The goal this research determine whether chronic administration aqueous extract fruit pulp dosages (100, 200, 400 mg/kg) have antidepressant effects. behavioural model rats when supplied over three four months in experimental rats. Wistar albino weighing 200 300 grams one two old were utilized. For all experiments, healthy wistar either sex separated into six groups with equal numbers animals. properties investigated using different methods. Both forced swimming tail suspension tests fall category. was given at doses 100 mg/kg, mg/kg. To treat depression, standard dose medication (10 imipramine administered. Each group tested hour after treatment. A rat stress paradigm found that nephroprotective effect. Antioxidant phytochemicals like extracted quantified. abundance implies might be good source antioxidants depression therapy. current evidence intriguing may employed as medicine candidate additional study clinical tests.